Nepicastat (free base)

Synonym: 173997-05-2; RS-25560-197; SYN117

CAS Number: 173997-05-2
PubChem CID: 9796181

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Nepicastat (free base) (SYN-117), soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins.

Molecular Weight

295.4

Molecular Formula

C₁₄H₁₅F₂N₃S

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 61 mg/mL (183.83 mM); Water: insoluble; Ethanol: insoluble

Applications

Nepicastat (free base) (SYN-117) can be used its effect on inhibiting the enzyme dopamine β-hydroxylase (DBH), which is involved in the conversion of dopamine to norepinephrine.