Properties
Description
Netupitant, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets neurokinin 1 receptor.
Molecular Formula
C30H32F6N4O
Targets
Neurokinin 1 receptor
Solubility
DMSO: 2 mg/mL (3.45 mM); Water: insoluble; Ethanol: 85 mg/mL (146.91 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Netupitant can be used for its ability to improve the control of CINV and enhance the overall quality of life for these patients.
Storage
Store at -20°C, and keep desiccated.