Properties
Description
JSH 23, soluble in DMSO and ethanol and insoluble in water, is a potent and specific inhibitor of NF-κB activation. It targets NFκB.
Molecular Formula
C16H20N2
Targets
NFκB: 7.1 μM (In raw 264.7 cells)
Solubility
DMSO: 41 mg/mL (170.59 mM); Water: Insoluble; Ethanol: 17 mg/mL (70.73 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
JSH 23 can be utilized to study its inhibition of NF-κB nuclear translocation and its effects on inflammation and cancer.