NF-κB inhibitor SC75741, Purity ≥98%

Synonym: SC75741; 913822-46-5; N-(6-Benzoyl-1H-benzimidazol-2-yl)-2-(1-thieno[3,2-d]pyrimidin-4-yl-4-piperidinyl)-4-Thiazolecarboxamide; SC-75741; N-(6-Benzoyl-1H-benzimidazol-2-yl)-2-(1-thieno[3,2-d]pyrimidin-4-yl-4-piperidinyl)-4-thiazolecarboxamide; N-(6-Benzoyl-1H-benzo[d]imidazol-2-yl)-2-(1-(thieno[3,2-d]pyrimidin-4-yl)piperidin-4-yl)thiazole-4-carboxamide; NF-κB inhibitor

CAS Number: 913822-46-5
Compound CID: 23661638

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SC75741, soluble in warmed DMSO and insoluble in water and ethanol, is a potent and specific inhibitor of NF-κB activation. It targets NFκB.

Molecular Weight

565.67

Molecular Formula

C₂₉H₂₃N₇O₂S₂

Targets

NFκB: 200 nM (EC₅₀)

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 35 mg/mL (61.87 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

SC75741 can be used to investigate its role as an NF-κB inhibitor in various inflammatory and autoimmune disease models.