NH125

Synonym: 278603-08-0; NH 125; 1-Benzyl-3-cetyl-2-methylimidazolium iodide

CAS Number: 278603-08-0
PubChem CID: 10436839

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NH125, soluble in DMSO and ethanol and insoluble in water, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets CaMKII, eEF-2 kinase, PKA, and PKC.

Molecular Weight

524.56

Molecular Formula

C₂₇H₄₅IN₂

Targets

CaMKII: >100 μM; eEF-2 kinase: 60 nM; PKA: 80 μM; PKC: 7.5 μM

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 89 mg/mL (169.66 mM); Water: insoluble; Ethanol: 89 mg/mL (169.66 mM)

Applications

NH125 can be used to help develop potential therapeutic strategies for certain diseases, such as inflammatory disease, fibrotic diseases, and cancer.