Properties
Description
Nitisinone, soluble in DMSO and insoluble in water and ethanol, is a competitive inhibitor that reversibly inhibits 4-hydroxyphenylpyruvate oxidase (dioxygenase). The molecular weight of the compound is 329.2, and its molecular formula is C14H10F3NO5.
Molecular Formula
C14H10F3NO5
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 62 mg/mL (188.32 mM); Water: insoluble; Ethanol: insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Nitisinone can be studied extensively for its potential therapeutic applications in the treatment of hereditary tyrosinemia type I.
