Properties
Description
2'-O-Methyl-N2-isobutyryl-5'-O-DMT-guanosine-3'-CE-phosphoramidite is a chemical reagent that enables the attachment of biologically active molecules to RNA or modified RNA molecules through a phosphoramidization reaction to form RNA drug splices.
Molecular Formula
C43H54N5O9P
Identity
Confirmed by NMR/HPLC/MS.
Applications
In drug discovery and development, 2'-O-methyl-N2-isobutyryl-5'-O-DMT-guanosine-3'-CE-phosphoramidite can be used to synthesize locked RNAs by matching exactly to a specific mRNA or miRNA.