Glycosphingolipid (GSLs) is a group of glycolipids consisting of a sugar group linked to neuro sphingomyelin and are commonly referred to as sphingolipids with sphingomyelin. CD BioGlyco has been committed to providing customers with high-quality organic solvent-based GSL extraction services, such as phenol-water extraction, ester extraction, and methanol extraction.
GSLs are distributed in the outer layer of the cell membrane, with nonpolar hydrocarbon long chains in the outer lipid layer and polar glycolipids extending into the extracellular aqueous phase. Very small amounts of GSLs are present in cells as intermediate carriers in the process of synthesizing glycolipids. GSLs are widely found in living organisms, including plants, animals, fungi, and bacteria. Among them, cerebroside and sphingomyelin are the major GSLs in brain tissue and play an important role in the normal function of the nervous system. In addition, GSLs are also involved in the occurrence and development of several diseases, such as tumors, autoimmune diseases, and inflammation. The study of GSLs helps to gain insight into the structure and function of biological membranes and the mechanism of related diseases, which is expected to provide new ideas for the prevention of diseases.
Fig.1 Structure of glycolipid. (Wikipedia)
We offer customized extraction services for GSLs using proven phenol water extraction strategies, and our services would shorten the experimental time and enable customers to obtain products faster.
We provide efficient and professional ether extraction service for GSL, which is widely present in many different types of biological samples, such as animals, plants, microorganisms, etc. This service allows for the extraction of a wide range of sample types, enabling the accurate separation of GSL from a wide range of substances with good applicability.
Our extraction service allows for the simultaneous extraction of multiple GSLs, as well as membrane proteins and GSLs, and is also suitable for the analysis of complexes on cell membranes.
Fig.2 One-stop GSL research at CD BioGlyco. (CD BioGlyco)
CD BioGlyco is a leader in the GSL extraction field. Our professional and experienced researchers are willing to provide high-quality and cost-effective organic solvent-based GSL extraction services to our customers. If you are interested in our services, please contact us to obtain more information.
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