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OC is a water-insoluble and acidic cellulose derivative. It contains 16% ~ 24% of carboxyl groups (COOH). OC has a wide range of applications in the medical field due to its unique acidity that triggers coagulation processes in organisms and its antibacterial properties. OC has the efficacy of anti-tumor, wound healing, immunostimulation, and prevention of adhesion. Therefore, CD BioGlyco offers detailed characterization and oxidation analysis of OC.
Fig.1 Tools of OC analysis. (CD BioGlyco)
Technology: FTIR, Potentiometric titration, XRD
Journal: Journal of Polymer Science Part A: Polymer Chemistry
Published: 2004
Results: In this study, researchers prepared OCs with different carboxylation amounts and different crystallinity by oxidizing natural and mercerized celluose by nitrogen (IV) oxide solution in carbon tetrachloride. The advantage of this method is that the vegetated samples have low index of crystallinity (IC) and degree of polymerization (DP) and high carboxylation content. Further characterization and oxidation analysis of the obtained OCs showed that oxidation takes place only in amorphous regions and on crystal surfaces. Detailed analysis of the physicochemical properties helped to evaluate the drug binding OC properties.
Fig.2 FTIR spectra of different oxidized cellulose. (Zimnitsky, et al., 2004)
CD BioGlyco provides the most appropriate analytic service for each Pharmaceutical and Biological. Depending on the molecular properties, we provide a full set of analytical services including conventional analysis, physical and chemical analysis, and biological activity analysis. Moreover, we provide Oxidized Regenerated Cellulose Analysis. Please feel free to contact us if you have additional questions about OC analysis.
References
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CD BioGlyco is a world-class biotechnology company with offices in many countries. Our products and services provide a viable option to what is otherwise available.
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