P-gp inhibitor KS-176, Purity ≥98%

Synonym: 1253452-78-6; P-gp inhibitor; KS176; KS 176

MDL: MFCD22666402
CAS Number: 1253452-78-6
Compound CID: 49779726

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

KS-176, soluble in DMSO and ethanol and insoluble in water, blocks the action of P-glycoprotein, a key player in drug transport and resistance, thereby enhancing the effectiveness and bioavailability of therapeutic drugs.

Molecular Weight

405.4

Molecular Formula

C₂₂H₁₉N₃O₅

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 75 mg/mL (185 mM); Water: Insoluble; Ethanol: 3 mg/mL (7.4 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

KS-176 is a P-gp inhibitor utilized in research concerning multidrug resistance and its impact on chemotherapy effectiveness.