P-gp inhibitor Tariquidar, Purity ≥98%

Synonym: 206873-63-4; P-gp inhibitor

MDL: MFCD09837824
CAS Number: 206873-63-4
Compound CID: 148201

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

Tariquidar, soluble in DMSO and insoluble in ethanol and water, blocks the action of P-glycoprotein, a key player in drug transport and resistance, thereby enhancing the effectiveness and bioavailability of therapeutic drugs. It targets P-gp (CHrB30 cells).

Molecular Weight

646.73

Molecular Formula

C₃₈H₃₈N₄O₆

Targets

P-gp (CHrB30 cells): 5.1 nM (Kd)

Form

Lyophilized powder

Purity

Solubility

DMSO: 48 mg/mL (74.22 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Tariquidar is a P-glycoprotein (P-gp) inhibitor used in research aimed at overcoming drug resistance in cancer therapy by blocking P-gp activity.