p38-MAPK inhibitor AMG 548, Purity ≥98%

Cat. No.: X23-10-ZQ892

p38-MAPK inhibitor AMG 548, Purity ≥98%

Synonym: AMG-548; 864249-60-5; AMG 548; CHEMBL585902; PGR0H531I4; 4(3H)-Pyrimidinone, 2-(((2S)-2-amino-3-phenylpropyl)amino)-3-methyl-5-(2-naphthalenyl)-6-(4-pyridinyl)-; 2-[[(2S)-2-Amino-3-phenylpropyl]amino]-3-methyl-5-(2-naphthalenyl)-6-(4-pyridinyl)-4(3H)-pyrimidinone; p38-MAPK inhibitor

  • CAS Number: 864249-60-5
  • Compound CID: 11167112
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
AMG 548 targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates.
Molecular Weight
461.56
Molecular Formula
C29H27N5O
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
AMG 548 can be used to investigate the inhibition of p38α MAP kinase and its therapeutic potential in inflammation.
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