p38-MAPK inhibitor BMS-582949, Purity ≥98%

Synonym: BMS-582949; 623152-17-0; BMS 582949; BMS582949; UNII-CR743OME9E; CR743OME9E; p38-MAPK inhibitor

MDL: MFCD18633248
CAS Number: 623152-17-0
Compound CID: 10409068

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BMS-582949, soluble in DMSO and insoluble in ethanol and water, targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates. It targets p38 MAPK.

Molecular Weight

406.49

Molecular Formula

C₂₂H₂₆N₆O₂

Targets

p38 MAPK: 13 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 79 mg/mL (194.35 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

BMS-582949 can be utilized in the study of selective p38α MAP kinase inhibition in inflammatory diseases.