p38-MAPK inhibitor FR 167653 free base, Purity ≥98%

Synonym: FR 167653 free base; 158876-65-4; 1-[7-(4-Fluorophenyl)-8-pyridin-4-yl-3,4-dihydro-1H-pyrazolo[5,1-c][1,2,4]triazin-2-yl]-2-phenylethane-1,2-dione; FR167653freebase; SCHEMBL7489352; p38-MAPK inhibitor

CAS Number: 158876-65-4
Compound CID: 135444724

Product Size

1 mg; 2 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

FR 167653 free base targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates.

Molecular Weight

427.43

Molecular Formula

C₂₄H₁₈FN₅O₂

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

FR 167653 free base is used to investigate its effects on inflammation and fibrosis through inhibition of p38 MAP kinase.

Storage

Store at -20ºC.