p38-MAPK inhibitor PD 169316, Purity ≥98%

Synonym: 152121-53-4; PD 169316; PD-169316; PD169316; 4-(4-(4-Fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl)pyridine; 4-[4-(4-Fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine; 4-(4-Fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)-1H-imidazole; p38-MAPK inhibitor

MDL: MFCD12405019
CAS Number: 152121-53-4
Compound CID: 4712

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PD 169316, soluble in DMSO and insoluble in ethanol and water, targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates.

Molecular Weight

360.3

Molecular Formula

C₂₀H₁₃FN₄O₂

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 12 mg/mL (33.3 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

PD 169316 is used to explore the selective inhibition of p38 MAP kinase and its role in cytokine production and inflammation.

Storage

Store at -20ºC.