Properties
Description
Ralimetinib, soluble in warmed DMSO, warmed water and ethanol, targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates.
Molecular Formula
C24H29FN6
Solubility
Warmed DMSO: 30 mg/mL (48.9 mM); Warmed water: 85 mg/mL (138.72 mM); Ethanol: 3 mg/mL (4.89 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Ralimetinib is investigated for its ability to inhibit p38 MAPK and its implications in treating inflammatory and oncological diseases.