p38-MAPK inhibitor RWJ-67657, Purity ≥98%

Synonym: RWJ-67657; 215303-72-3; RWJ 67657; 4-(4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl)but-3-yn-1-ol; 4-[4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol; p38-MAPK inhibitor

CAS Number: 215303-72-3
Compound CID: 3008319

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

RWJ-67657 targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates.

Molecular Weight

425.49736

Molecular Formula

C₂₇H₂₄FN₃O

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

RWJ-67657 can be used to analyze the effects of p38 MAP kinase inhibition in inflammation and cancer therapy.