p53 activator JNJ 26854165, Purity ≥98%

Synonym: 881202-45-5; Serdemetan; JNJ-26854165; JNJ-26854165 (Serdemetan); JNJ 26854165; Serdemetan [INN]; N1-(2-(1H-Indol-3-yl)ethyl)-N4-(pyridin-4-yl)benzene-1,4-diamine; p53 activator

MDL: MFCD16620518
CAS Number: 881202-45-5
Compound CID: 11609586

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

JNJ 26854165, soluble in DMSO and ethanol and insoluble in water, is a potent and selective p53-activating compound.

Molecular Weight

328.4

Molecular Formula

C₂₁H₂₀N₄

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 56 mg/mL (170.51 mM); Water: Insoluble; Ethanol: 2 mg/mL (6.08 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

JNJ 26854165 can be used to inhibit the MDM2-p53 interaction, promoting p53-mediated apoptosis in cancer research.