p53 activator NSC 319726, Purity ≥98%

Synonym: 71555-25-4; NSC319726; NSC 319726; N'-(1-(Pyridin-2-yl)ethylidene)azetidine-1-carbothiohydrazide; N-[(E)-1-Pyridin-2-ylethylideneamino]azetidine-1-carbothioamide; p53 activator

CAS Number: 71555-25-4
Compound CID: 5351307

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NSC 319726, soluble in DMSO and insoluble in ethanol and water, is a potent and selective p53-activating compound. It targets p53 (R175).

Molecular Weight

234.32

Molecular Formula

C₁₁H₁₄N₄S

Targets

p53 (R175): 8 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 17 mg/mL (72.55 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

NSC 319726 can be used to study the reactivation of mutant p53, aiding in the development of cancer treatments.

Storage

Store at -20ºC.