p53 activator NSC 319726, Purity ≥98%

Synonym: 71555-25-4; NSC319726; NSC 319726; N'-(1-(Pyridin-2-yl)ethylidene)azetidine-1-carbothiohydrazide; N-[(E)-1-Pyridin-2-ylethylideneamino]azetidine-1-carbothioamide; p53 activator

CAS Number: 71555-25-4
Compound CID: 5351307

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NSC 319726, soluble in DMSO and insoluble in ethanol and water, is a potent and selective p53-activating compound. It targets p53 (R175).

Molecular Weight

234.32

Molecular Formula

C₁₁H₁₄N₄S

Targets

p53 (R175): 8 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 17 mg/mL (72.55 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

NSC 319726 can be used to study the reactivation of mutant p53, aiding in the development of cancer treatments.