p53 activator NSC59984, Purity ≥98%

Synonym: 803647-40-7; NSC 59984; NSC59984; (E)-1-(4-Methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one; (E)-1-(4-Methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one; p53 activator

MDL: MFCD29905462
CAS Number: 803647-40-7
Compound CID: 5356520

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NSC59984, soluble in DMSO and ethanol and insoluble in water, is a potent and selective p53-activating compound. It targets p53.

Molecular Weight

265.27

Molecular Formula

C₁₂H₁₅N₃O₄

Targets

p53

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 48 mg/mL (180.94 mM); Water: Insoluble; Ethanol: 48 mg/mL (180.94 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

NSC59984 can be used to reactivate mutant p53, providing a tool for research into targeted cancer therapies.

Storage

Store at -20ºC.