p53 activator PK11007, Purity ≥98%

Synonym: 38275-34-2; PK11000; 5-Chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid; 5-Chloro-2-(methylsulfonyl)-4-pyrimidinecarboxylic acid; p53 activator

MDL: MFCD00507244
CAS Number: 38275-34-2
Compound CID: 1241459

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PK11007, soluble in DMSO, water and ethanol, is a potent and selective p53-activating compound.

Molecular Weight

236.63

Molecular Formula

C₆H₅ClN₂O₄S

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 46 mg/mL (194.39 mM); Water: 46 mg/mL (194.39 mM); Ethanol: 23 mg/mL (97.19 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

PK11007 can be used to stabilize p53, aiding in studies on the rescue of p53 function in cancer cells.

Storage

Store at -20ºC.