p53 activator PK11007, Purity ≥98%

Synonym: 38275-34-2; PK11000; 5-Chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid; 5-Chloro-2-(methylsulfonyl)-4-pyrimidinecarboxylic acid; p53 activator

MDL: MFCD00507244
CAS Number: 38275-34-2
Compound CID: 1241459

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PK11007, soluble in DMSO, water and ethanol, is a potent and selective p53-activating compound.

Molecular Weight

236.63

Molecular Formula

C₆H₅ClN₂O₄S

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 46 mg/mL (194.39 mM); Water: 46 mg/mL (194.39 mM); Ethanol: 23 mg/mL (97.19 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

PK11007 can be used to stabilize p53, aiding in studies on the rescue of p53 function in cancer cells.