p53 activator PRIMA-1, Purity ≥98%

Synonym: 5608-24-2; NSC-281668; NSC281668; Prima-1; 2,2-Bis(hydroxymethyl)-3-quinuclidinone; 2,2-Bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one; p53 activator

MDL: MFCD19199989
CAS Number: 5608-24-2
Compound CID: 322968

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PRIMA-1, soluble in DMSO, water and ethanol, is a potent and selective p53-activating compound. It targets mutant p53.

Molecular Weight

185.22

Molecular Formula

C₉H₁₅NO₃

Targets

Mutant p53

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 37 mg/mL (199.76 mM); Water: 37 mg/mL (199.76 mM); Ethanol: 37 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

PRIMA-1 is utilized to restore the function of mutant p53 in cancer research, thereby inducing apoptosis in tumor cells.

Storage

Store at -20ºC.