p53 activator Tenovin-6, Purity ≥98%

Synonym: Tenovin-6; 1011557-82-6; Tenovin 6; 4-tert-Butyl-N-[[4-[5-(dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide; p53 activator

MDL: MFCD11976906
CAS Number: 1011557-82-6
Compound CID: 24772043

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Tenovin-6, soluble in DMSO and warmed water and insoluble in ethanol, is a potent and selective p53-activating compound. It targets p53, SIRT2, SIRT1, and SIRT3.

Molecular Weight

454.6

Molecular Formula

C₂₅H₃₄N₄O₂S

Targets

p53; SIRT2: 10 μM; SIRT1: 21 μM; SIRT3: 63 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 87 mg/mL (191.36 mM); Warmed water: 87 mg/mL (191.36 mM); Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Tenovin-6 can be used to activate p53 and inhibit sirtuins, providing a tool for research into cancer therapies.