p53 inhibitor CBL-0137, Purity ≥98%

Synonym: 1197397-89-9; CBL0137 hydrochloride; cblc137 hydrochloride; UNII-FOY14S7DFX; FOY14S7DFX; CBL-C137 hydrochloride; Curaxin-137 hydrochloride; p53 inhibitor

CAS Number: 1197397-89-9
Compound CID: 44519123

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CBL-0137, soluble in DMSO and water and insoluble in ethanol, is a potent and selective p53-activating compound.

Molecular Weight

372.89

Molecular Formula

C₂₁H₂₄N₂O₂.HCl

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 35 mg/mL (93.86 mM); Water: 22 mg/mL (59 mM); Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

CBL-0137 can be used to activate p53 and inhibit NF-κB, offering potential insights into cancer and inflammation research.