Cat. No.: X23-10-ZQ101
p53 inhibitor NSC348884, Purity ≥98%
Synonym: 81624-55-7; NSC348884; NSC 348884; NSC-348884; NSC348884 hydrate; N,N,N',N'-Tetrakis[(6-methyl-1H-benzimidazol-2-yl)methyl]ethane-1,2-diamine; N1,N1,N2,N2-Tetrakis((6-methyl-1H-benzo[d]imidazol-2-yl)methyl)ethane-1,2-diamine; p53 inhibitor
- CAS Number: 81624-55-7
- Compound CID: 335974
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
NSC348884, soluble in DMSO and ethanol and insoluble in water, is an inhibitor of p53-mediated apoptosis and p53-dependent gene transcription. It targets nucleophosmin.
Solubility
DMSO: 92 mg/mL (144.47 mM); Water: Insoluble; Ethanol: 92 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
NSC348884 can be employed to investigate the disruption of nucleophosmin (NPM1) oligomerization and its effects on cancer cell proliferation.
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