Cat. No.: X23-10-ZQ101
p53 inhibitor NSC348884, Purity ≥98%
Synonym: 81624-55-7; NSC348884; NSC 348884; NSC-348884; NSC348884 hydrate; N,N,N',N'-Tetrakis[(6-methyl-1H-benzimidazol-2-yl)methyl]ethane-1,2-diamine; N1,N1,N2,N2-Tetrakis((6-methyl-1H-benzo[d]imidazol-2-yl)methyl)ethane-1,2-diamine; p53 inhibitor
- CAS Number: 81624-55-7
- Compound CID: 335974
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
NSC348884, soluble in DMSO and ethanol and insoluble in water, is an inhibitor of p53-mediated apoptosis and p53-dependent gene transcription. It targets nucleophosmin.
Solubility
DMSO: 92 mg/mL (144.47 mM); Water: Insoluble; Ethanol: 92 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
NSC348884 can be employed to investigate the disruption of nucleophosmin (NPM1) oligomerization and its effects on cancer cell proliferation.
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