p53 inhibitor Pifithrin-alpha, Purity ≥98%

Synonym: 63208-82-2; Pifithrin-alpha; PFT-alpha; Pifithrin-alpha hydrobromide; Pifithrin hydrobromide; 2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone hydrobromide; p53 inhibitor

MDL: MFCD00417851
CAS Number: 63208-82-2
Compound CID: 9929138

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Pifithrin-alpha, soluble in DMSO and insoluble in ethanol and water, is an inhibitor of p53-mediated apoptosis and p53-dependent gene transcription. It targets p53.

Molecular Weight

367.3

Molecular Formula

C₁₆H₁₈N₂OS.HBr

Targets

p53

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 58 mg/mL (157.91 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Pifithrin-alpha can be used to reversibly inhibit p53, aiding research in the regulation of p53-dependent apoptosis.