p53 inhibitor Pifithrin-beta, Purity ≥98%

Synonym: 511296-88-1; Cyclic pifithrin-alpha hydrobromide; Pifithrin-beta hydrobromide; Cyclic Pifithrin-|A hydrobromide; Pifithrin-beta HBr; UP003XXT4D; Pifithrin-b; 5,6,7,8-Tetrahydro-2-(4-methylphenyl)imidazo(2,1-b)benzothiazole hydrobromide; p53 inhibitor

MDL: MFCD02683960
CAS Number: 511296-88-1
Compound CID: 11515812

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Pifithrin-beta, soluble in DMSO and ethanol and insoluble in water, is an inhibitor of p53-mediated apoptosis and p53-dependent gene transcription.

Molecular Weight

349.29

Molecular Formula

C₁₆H₁₆N₂S.HBr

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 24 mg/mL (68.7 mM); Water: Insoluble; Ethanol: 3 mg/mL (8.58 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Pifithrin-beta can be used to inhibit p53 transcriptional activity, providing a tool for studying p53-related pathways.

Storage

Store at -20ºC.