p53 inhibitor Pifithrin-u, Purity ≥98%

Synonym: 64984-31-2; Pifithrin-mu; 2-Phenylethynesulfonamide; 2-Phenylacetylenesulfonamide; Pifithrin-|I; Phenylethynesulfonamide; Pifithrin-micro; p53 inhibitor

MDL: MFCD00181531
CAS Number: 64984-31-2
Compound CID: 327653

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Pifithrin-u, soluble in DMSO and ethanol and insoluble in water, is an inhibitor of p53-mediated apoptosis and p53-dependent gene transcription. It targets p53.

Molecular Weight

181.21

Molecular Formula

C₈H₇NO₂S

Targets

p53

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 33 mg/mL (182.11 mM); Water: Insoluble; Ethanol: 33 mg/mL (182.11 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Pifithrin-u can be used to inhibit p53, exploring the role of p53 in stress responses and neuroprotection.

Storage

Store at -20ºC.