Properties
Description
FRAX1036, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting PAK. It targets the PAK1, PAK2, and PAK4.
Molecular Formula
C28H32ClN7O
Targets
PAK1: 23.3 nM (Ki); PAK2: 72.4 nM (Ki); PAK4: 2.4 μM (Ki)
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: insoluble; Water: insoluble; Ethanol: 17 mg/mL (32.81 mM)
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
FRAX1036 is a cytoskeletal signaling inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of cancers by targeting the PAK1 pathway involved in cell proliferation and survival.
Storage
Store at -20ºC, and keep desiccated.
