Properties
Description
FRAX486, soluble in DMSO and insoluble in water and ethanol, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting PAK. It targets the PAK1, PAK2, PAK3, and PAK4.
Molecular Formula
C25H23Cl2FN6O
Targets
PAK1: 14 nM; PAK2: 33 nM; PAK3: 39 nM; PAK4: 575 nM
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 21 mg/mL (40.9 mM); Water: insoluble; Ethanol: insoluble
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
FRAX486 is a cytoskeletal signaling inhibitor that plays a key role in cell growth, motility, and survival.
Storage
Store at -20ºC, and keep desiccated.
