PAK inhibitor, FRAX597, Purity ≥98%

Cat. No.: X24-08-YM268

PAK inhibitor, FRAX597, Purity ≥98%

Synonym: 1286739-19-2; FRAX 597; FRAX-597; 6-[2-Chloro-4-(1,3-thiazol-5-yl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one

  • MDL: MFCD25976723
  • CAS Number: 1286739-19-2
  • Compound CID: 70934541
Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
MSDS
Properties
Description
FRAX597, soluble in warmed DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting PAK. It targets the PAK1, PAK2, PAK2, and PAK3.
Molecular Weight
558.1
Molecular Formula
C29H28ClN7OS
Targets
PAK1: 8 nM; PAK2: 13 nM; PAK2: 13 nM; PAK3: 19 nM
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO (warmed): 13 mg/mL (23.29 mM); Water: insoluble; Ethanol: 1 mg/mL (1.79 mM)
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
FRAX597 is a cytoskeletal signaling inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of cancers and other diseases where PAK1 plays a critical role.
Storage
Store at -20ºC, and keep desiccated.
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