PAK inhibitor, G-5555, Purity ≥98%

Synonym: 1648863-90-4; G5555; G 5555; 8-[(5-Amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one

CAS Number: 1648863-90-4
Compound CID: 91664373

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

G-5555 is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting PAK. It targets the PAK1 and PAK2.

Molecular Weight

492.96

Molecular Formula

C₂₅H₂₅ClN₆O₃

Targets

PAK1: 3.7 nM (Ki); PAK2: 11 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Applications

G-5555 is a cytoskeletal signaling inhibitor that can be used for its potential to induce apoptosis in cancer cells by inhibiting Mcl-1, which is often overexpressed in tumors.