Properties
Description
KPT 9274, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting PAK.
Molecular Formula
C35H29F3N4O3
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 85 mg/mL (139.2 mM); Water: insoluble; Ethanol: 85 mg/mL (139.2 mM)
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
KPT 9274 is a cytoskeletal signaling inhibitor that can be used for its ability to inhibit the export of tumor suppressor proteins and other key regulators from the nucleus to the cytoplasm, which can enhance antitumor activity.
Storage
Store at -20ºC, and keep desiccated.
