Properties
Description
Pamidronate disodium, insoluble in DMSO and ethanol and soluble in water, is a nitrogen containing bisphosphonate. The molecular weight of the compound is 279.03, and its molecular formula is C3H9NNa2O7P2.
Molecular Formula
C3H9NNa2O7P2
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: insoluble; Water: 50 mg/mL (179.19 mM); Ethanol: insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Pamidronate disodium can be studied extensively for its potential therapeutic applications in the treatment of hypercalcemia associated with malignancy and Paget’s disease of bone.