PARP inhibitor AG-014699, Purity ≥98%

Synonym: 459868-92-9; Rucaparib phosphate; AG-014699; PF-01367338; AG014699; AG 014699; Rucaparib (phosphate); PARP inhibitor

MDL: MFCD17010269
CAS Number: 459868-92-9
Compound CID: 9931953

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AG-014699, soluble in DMSO and insoluble in ethanol and water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks. It targets PARP.

Molecular Weight

421.4

Molecular Formula

C₁₉H₁₈FN₃O.H₃PO₄

Targets

PARP: 1.4 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 81 mg/mL (192.23 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

AG-014699 can be used to explore its potential as a PARP inhibitor in enhancing chemotherapy.