PARP inhibitor AZ6102, Purity ≥98%

Synonym: 1645286-75-4; AZ6102; AZ-6102; AZ 6102; 2-(4-(6-((3R,5S)-3,5-Dimethylpiperazin-1-yl)-4-methylpyridin-3-yl)phenyl)-7-methyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one; PARP inhibitor

CAS Number: 1645286-75-4
Compound CID: 135905416

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AZ6102, soluble in DMSO and insoluble in ethanol and water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks. It targets TNKS1 and TNKS2.

Molecular Weight

428.53

Molecular Formula

C₂₅H₂₈N₆O

Targets

TNKS1; TNKS2

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 83 mg/mL (193.68 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

AZ6102 can be used to investigate the inhibition of tankyrase and its effects on Wnt/β-catenin signaling in cells.

Storage

Store at -20ºC.