PARP inhibitor AZD-2461, Purity ≥98%

Synonym: 1174043-16-3; AZD2461; 3K288XF5XJ; AZD-2461; 4-(4-Fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one; PARP inhibitor

MDL: MFCD24386811
CAS Number: 1174043-16-3
Compound CID: 44199317

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AZD-2461, soluble in DMSO and ethanol and insoluble in water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks. It targets PARP.

Molecular Weight

395.43

Molecular Formula

C₂₂H₂₂FN₃O₃

Targets

PARP

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 73 mg/mL (184.61 mM); Water: Insoluble; Ethanol: 29 mg/mL (73.33 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

AZD-2461 can be used to study its role as a PARP inhibitor in cancer therapy.

Storage

Store at -20ºC.