PARP inhibitor BMN673, Purity ≥98%

Synonym: 1207456-01-6; Talazoparib; BMN-673; BMN 673; BMN673; Talazoparib (BMN 673); Talzenna; PARP inhibitor

MDL: MFCD22666357
CAS Number: 1207456-01-6
Compound CID: 135565082

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BMN673, soluble in warmed DMSO and insoluble in water and ethanol, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks. It targets PARP.

Molecular Weight

380.35

Molecular Formula

C₁₉H₁₄F₂N₆O

Targets

PARP: 0.58 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 38 mg/mL (99.9 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

BMN673 can be used to investigate its effects as a potent PARP inhibitor.

Storage

Store at -20ºC.