Properties
Description
BYK 204165, soluble in DMSO and insoluble in ethanol and water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks.
Molecular Formula
C15H12N2O2
Solubility
DMSO: 46 mg/mL (182.34 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
BYK 204165 can be used to study the inhibition of PARP and its consequences on cellular processes.