PARP inhibitor EB 47, Purity ≥98%

Synonym: 1190332-25-2; EB 47; 2-[4-[(2S,3R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolane-2-carbonyl]piperazin-1-yl]-N-(1-oxo-2,3-dihydroisoindol-4-yl)acetamide; PARP inhibitor

CAS Number: 1190332-25-2
Compound CID: 124080891

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

EB 47 binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks.

Molecular Weight

610.45

Molecular Formula

C₂₄H₂₇N₉O₆.2HCl

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

EB 47 can be used to investigate the inhibition of protein arginine methyltransferase 5 (PRMT5) in cancer cell lines.