PARP inhibitor EB 47, Purity ≥98%

Synonym: 1190332-25-2; EB 47; 2-[4-[(2S,3R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolane-2-carbonyl]piperazin-1-yl]-N-(1-oxo-2,3-dihydroisoindol-4-yl)acetamide; PARP inhibitor

CAS Number: 1190332-25-2
Compound CID: 124080891

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

EB 47 binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks.

Molecular Weight

610.45

Molecular Formula

C₂₄H₂₇N₉O₆.2HCl

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

EB 47 can be used to investigate the inhibition of protein arginine methyltransferase 5 (PRMT5) in cancer cell lines.

Storage

Store at -20ºC.