PARP inhibitor G007-LK, Purity ≥98%

Synonym: 1380672-07-0; G007-LK; (E)-4-(5-(2-(4-(2-Chlorophenyl)-5-(5-(methylsulfonyl)pyridin-2-yl)-4H-1,2,4-triazol-3-yl)vinyl)-1,3,4-oxadiazol-2-yl)benzonitrile; PARP inhibitor

CAS Number: 1380672-07-0
Compound CID: 67960134

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

G007-LK, soluble in DMSO and insoluble in ethanol and water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks.

Molecular Weight

529.96

Molecular Formula

C₂₅H₁₆ClN₇O₃S

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 98 mg/mL (184.92 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

G007-LK can be used to study the inhibition of tankyrase and its effects on the Wnt/β-catenin pathway.

Storage

Store at -20ºC.