Properties
Description
GeA-69, soluble in DMSO and ethanol and insoluble in water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks.
Molecular Formula
C20H16N2O
Solubility
DMSO: 52 mg/mL (173.13 mM); Water: Insoluble; Ethanol: 9 mg/mL (29.96 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
GeA-69 can be used to explore its role as an inhibitor of tankyrase, impacting Wnt/β-catenin signaling.