PARP inhibitor JW 55, Purity ≥98%

Synonym: 664993-53-7; jw55; JW 55; JW-55; N-(4-(((4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)methyl)carbamoyl)phenyl)furan-2-carboxamide; PARP inhibitor

MDL: MFCD03863265
CAS Number: 664993-53-7
Compound CID: 2946601

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

JW 55, soluble in DMSO and ethanol and insoluble in water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks.

Molecular Weight

434.48

Molecular Formula

C₂₅H₂₆N₂O₅

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 79 mg/mL (181.82 mM); Water: Insoluble; Ethanol: 4 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

JW 55 can be used to research the inhibition of tankyrase in the Wnt signaling pathway.

Storage

Store at -20ºC.