Properties
Description
MN-64, soluble in DMSO and ethanol and insoluble in water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks.
Molecular Formula
C18H16O2
Solubility
DMSO: 46 mg/mL (174.03 mM); Water: Insoluble; Ethanol: 46 mg/mL (174.03 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
MN-64 can be used to study the inhibition of tankyrase and its potential as a cancer therapeutic.