PARP inhibitor Niraparib, Purity ≥98%

Synonym: 1038915-60-4; Niraparib; MK-4827; (S)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide; MK4827; PARP inhibitor

MDL: MFCD17779309
CAS Number: 1038915-60-4
Compound CID: 24958200

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Niraparib, soluble in DMSO and ethanol and insoluble in water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks.

Molecular Weight

320.4

Molecular Formula

C₁₉H₂₀N₄O

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 60 mg/mL (187.27 mM); Water: Insoluble; Ethanol: 60 mg/mL (187.27 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Niraparib can be used to research its role as a PARP inhibitor in ovarian cancer therapy.