PARP inhibitor Niraparib tosylate, Purity ≥98%

Synonym: 1038915-73-9; MK-4827 tosylate; Niraparib tosylate; MK-4827 (tosylate); MK-4827-tosylate; UNII-75KE12AY9U; (S)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide 4-methylbenzenesulfonate; PARP inhibitor

CAS Number: 1038915-73-9
Compound CID: 78357761

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Niraparib tosylate, soluble in DMSO and insoluble in ethanol and water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks.

Molecular Weight

492.59

Molecular Formula

C₂₆H₂₈N₄O₄S

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 86 mg/mL (174.58 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Niraparib tosylate can be used to study its effects as a PARP inhibitor in cancer therapy.

Storage

Store at -20ºC.