PARP inhibitor NMS-P118, Purity ≥98%

Synonym: 1262417-51-5; NMS-P118; 2-[1-(4,4-Difluorocyclohexyl)-piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide; PARP inhibitor

CAS Number: 1262417-51-5
Compound CID: 49843531

Product Size

2 mg; 5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NMS-P118, soluble in warmed DMSO and warmed ethanol and insoluble in water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks.

Molecular Weight

395.42

Molecular Formula

C₂₀H₂₄F₃N₃O₂

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 22 mg/mL (55.63 mM); Water: Insoluble; Warmed ethanol: 5 mg/mL (12.64 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

NMS-P118 can be used to investigate its role as a JAK2 inhibitor for therapeutic purposes.