Properties
Description
NU 1025, soluble in DMSO and warmed ethanol and insoluble in water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks. It targets PARP.
Molecular Formula
C9H8N2O2
Solubility
DMSO: 34 mg/mL (192.99 mM); Water: Insoluble; Warmed ethanol: 6 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
NU 1025 can be used as an inhibitor of PARP to study its role in DNA repair and cell death.