PARP inhibitor NU 1025, Purity ≥98%

Synonym: 90417-38-2; NU1025; Nu 1025; 8-Hydroxy-2-methylquinazolin-4(3H)-one; 8-Hydroxy-2-methylquinazoline-4-one; PARP inhibitor

CAS Number: 90417-38-2
Compound CID: 135398517

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NU 1025, soluble in DMSO and warmed ethanol and insoluble in water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks. It targets PARP.

Molecular Weight

176.2

Molecular Formula

C₉H₈N₂O₂

Targets

PARP: 400 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 34 mg/mL (192.99 mM); Water: Insoluble; Warmed ethanol: 6 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

NU 1025 can be used as an inhibitor of PARP to study its role in DNA repair and cell death.