Properties
Description
PJ 34 hydrochloride, soluble in DMSO and water and insoluble in ethanol, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks.
Molecular Formula
C17H17N3O2.HCl
Solubility
DMSO: 57 mg/mL (171.79 mM); Water: 57 mg/mL (171.79 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
PJ 34 hydrochloride can be used to study its role as a PARP inhibitor in apoptosis.