PARP inhibitor, Rucaparib, Purity ≥98%

Synonym: 283173-50-2; Rucaparib free base; AG-014699; PF-01367338; AG 014699; PF 01367338; AG014699; PF01367338; 6-Fluoro-2-[4-(methylaminomethyl)phenyl]-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-9-one

MDL: MFCD11977252
CAS Number: 283173-50-2
Compound CID: 9931954

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Rucaparib is an effective DNA damage inhibitor, that has the ability to prevent the pathway of epigenetics by inhibiting PARP. It targets the PARP-1.

Molecular Weight

323.4

Molecular Formula

C₁₉H₁₈FN₃O

Targets

PARP-1: 1.4 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Applications

Rucaparib is an epigenetic inhibitor that plays a key role in the accumulation of DNA damage in cancer cells that are already deficient in DNA repair.